Education
- PhD, 2006, University of California, Berkeley
- BS, 2000, Biology and Genetics, Cornell University
Research Summary
We study how cells and tissues change shape during embryonic development, giving rise to different body parts. We visualize these changes to determine how mechanical forces drive massive tissue movements in the fruit fly, Drosophila melanogaster. In addition, we also study the regulation of tissue integrity, investigating the processes that regulate the epithelial-to-mesenchymal transition or EMT.Recent Publications
- Change in RhoGAP and RhoGEF availability drives transitions in cortical patterning and excitability in Drosophila. Jackson, JA, Denk-Lobnig, M, Kitzinger, KA, Martin, AC. 2024. Curr Biol 34, 2132-2146.e5.
doi: 10.1016/j.cub.2024.04.021PMID:38688282 - Morphogenesis: Setting the pace of embryo folding. Clarke, DN, Martin, AC. 2024. Curr Biol 34, R286-R288.
doi: 10.1016/j.cub.2024.02.053PMID:38593774 - Drosophila Fog/Cta and T48 pathways have overlapping and distinct contributions to mesoderm invagination. Horo, U, Clarke, DN, Martin, AC. 2024. Mol Biol Cell 35, ar69.
doi: 10.1091/mbc.E24-02-0050PMID:38536475 - EGFR-dependent actomyosin patterning coordinates morphogenetic movements between tissues. Clarke, DN, Martin, AC. 2023. bioRxiv , .
doi: 10.1101/2023.12.22.573057PMID:38187543 - Change in RhoGAP and RhoGEF availability drives transitions in cortical patterning and excitability in Drosophila. Jackson, JA, Denk-Lobnig, M, Kitzinger, KA, Martin, AC. 2023. bioRxiv , .
doi: 10.1101/2023.11.06.565883PMID:37986763 - Live Imaging of Nurse Cell Behavior in Late Stages of Drosophila Oogenesis. Jackson, JA, Imran Alsous, J, Martin, AC. 2023. Methods Mol Biol 2626, 219-232.
doi: 10.1007/978-1-0716-2970-3_11PMID:36715907 - Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation. Camuglia, J, Chanet, S, Martin, AC. 2022. Elife 11, .
doi: 10.7554/eLife.78779PMID:35796436 - Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics. Khetan, R, Curtis, R, Deane, CM, Hadsund, JT, Kar, U, Krawczyk, K, Kuroda, D, Robinson, SA, Sormanni, P, Tsumoto, K et al.. 2022. MAbs 14, 2020082.
doi: 10.1080/19420862.2021.2020082PMID:35104168 - Combinatorial patterns of graded RhoA activation and uniform F-actin depletion promote tissue curvature. Denk-Lobnig, M, Totz, JF, Heer, NC, Dunkel, J, Martin, AC. netbet sports betting2021. Development 148, .
doi: 10.1242/dev.199232PMID:34124762 - Actin-based force generation and cell adhesion in tissue morphogenesis. Clarke, DN, Martin, AC. 2021. Curr Biol 31, R667-R680.
doi: 10.1016/j.cub.2021.03.031PMID:34033797